Kahn R A, Staggs S D, Miller W V, Ellis F R
JAMA. 1979 Nov 9;242(19):2087-90.
During the past five years, there has been a sharp increase in the use of packed RBCs (PRBCs) and plasma products, whereas whole blood (WB) transfusions have steadily decreased. In order to determine whether plasma and its derivatives were being used to "reconstitute" whole blood from PRBCs, we performed a retrospective evaluation of all transfusion episodes in ten representative regional hospitals during a five-month period. Our results indicate that PRBCs were transfused 2.5 times more frequently than WB. Plasma products were administered with PRBCs less often than with WB: 14% of all PRBCs vs 24% of all WB units tranfused. The likelihood of a patient receiving plasma was found to correlate with the total amount of blood transfused and the frequency of transfusion. This study provides evidence that, at most, only a small percentage of PRBCs are given in conjunction with plasma as "reconstituted" WB.
在过去五年中,浓缩红细胞(PRBCs)和血浆制品的使用急剧增加,而全血(WB)输注则稳步减少。为了确定血浆及其衍生物是否被用于从PRBCs“重构”全血,我们对十家代表性地区医院在五个月期间的所有输血事件进行了回顾性评估。我们的结果表明,PRBCs的输注频率是WB的2.5倍。血浆制品与PRBCs一起使用的频率低于与WB一起使用的频率:所有输注的PRBCs中有14%,而所有WB单位中有24%。发现患者接受血浆的可能性与输血总量和输血频率相关。这项研究提供的证据表明,最多只有一小部分PRBCs与血浆一起作为“重构”的WB输注。