Crossley K, Irvine P, Warren J B, Lee B K, Mead K
JAMA. 1979 Nov 23;242(21):2298-300.
Tetanus and diphtheria antitoxin levels were measured in 183 urban adults, using a hemagglutination technique. Protective levels (greater than 0.01 unit/mL) of tetanus antitoxin were present in more than 85% of sera from all subjects under 40 years of age and from men between 40 and 59 years old. A minority of women (36%) between 40 and 59 years of age, and of men (41%) and women (29%) over 60 years of age, were protected. Less than one quarter of the study group had protective levels (greater than 0.01 unit/mL) of diphtheria antitoxin. The results of the study suggest that a minority of middle-aged women and older adults have been appropriately immunized against diphtheria and tetanus.
采用血凝技术检测了183名城市成年人的破伤风和白喉抗毒素水平。40岁以下所有受试者以及40至59岁男性中,超过85%的血清破伤风抗毒素水平达到保护水平(大于0.01单位/毫升)。40至59岁的少数女性(36%)以及60岁以上的男性(41%)和女性(29%)受到了保护。研究组中不到四分之一的人白喉抗毒素水平达到保护水平(大于0.01单位/毫升)。研究结果表明,少数中年女性和老年人对白喉和破伤风进行了适当免疫。