儿童对白喉、破伤风和脊髓灰质炎的免疫力。
Immunity of children to diphtheria, tetanus, and poliomyelitis.
作者信息
Bainton D, Freeman M, Magrath D I, Sheffield F, Smith J W
出版信息
Br Med J. 1979 Mar 31;1(6167):854-7. doi: 10.1136/bmj.1.6167.854.
A survey of titres of diphtheria and tetanus antitoxins and of antibodies to polioviruses in the sera of 291 schoolchildren aged 15, 11, and 7 years showed that high immunisation rates can evoke protective concentrations of tetanus antitoxin in 98% of children and protective levels of the antibodies to diphtheria and all three types of poliomyelitis in 85% of children. Reinforcing immunisation at school entry appeared to be necessary to maintain adequate titres of diphtheria antitoxin in children up to 15 years of age, not essential to maintain adequate titres of tetanus antitoxin, and to have little effect on the titres of antibodies to poliomyelitis.
一项针对291名15岁、11岁和7岁学童血清中白喉和破伤风抗毒素滴度以及脊髓灰质炎病毒抗体的调查显示，高免疫接种率可使98%的儿童产生保护性浓度的破伤风抗毒素，85%的儿童产生白喉和所有三种脊髓灰质炎类型抗体的保护水平。入学时加强免疫对于维持15岁以下儿童白喉抗毒素的足够滴度似乎是必要的，对于维持破伤风抗毒素的足够滴度并非必不可少，且对脊髓灰质炎抗体滴度影响不大。
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