Phadke A G, MacKinnon K J, Dossetor J B
Can Med Assoc J. 1970 Mar 28;102(6):607-8.
Spermatogenesis has been studied in eight chronic uremic patients on hemodialysis and in 11 recipients of well-functioning renal allografts. Sexual activity, semen analysis and testicular biopsy are abnormal in chronic uremic patients. Spermatogenesis remains "arrested" even when uremia is well controlled by intermittent hemodialysis. Marked improvement occurs in sexual performance, semen analysis and testicular biopsy after successful kidney transplantation. Immunosuppressive treatment, at dosages used six months after allografting, does not appear to affect male fertility adversely.
对8名接受血液透析的慢性尿毒症患者以及11名肾功能良好的肾移植受者的精子发生情况进行了研究。慢性尿毒症患者的性活动、精液分析和睾丸活检均存在异常。即使通过间歇性血液透析很好地控制了尿毒症，精子发生仍处于“停滞”状态。肾移植成功后，性功能、精液分析和睾丸活检有显著改善。移植后6个月使用的免疫抑制治疗剂量似乎不会对男性生育能力产生不利影响。
