Rittenberg S C, Shilo M
J Bacteriol. 1970 Apr;102(1):149-60. doi: 10.1128/jb.102.1.149-160.1970.
The effects of bdellovibrio infection on host permeability and respiration were investigated by measuring respiration rates and the rate of o-nitrophenyl-beta-d-galactopyranoside hydrolysis during the course of single infection cycles of Bdellovibrio bacteriovorus strain 109 growing on Escherichia coli ML 35 (lac i(-)z(+)y(-)). The data show that among the very early consequences of parasite attack on the host are an increase in permeability and a general disruption of respiratory activity of the host, and it is suggested that both phenomena stem from early damage to host membrane. The rapid onset of damage after inception of the cycle and the failure of streptomycin to prevent the damage indicate that complete penetration of the parasite into the host is not a requirement for the observed effects. The data also show that bdellovibrio does not use host energy-generating mechanisms for its growth and suggest that the parasites may have a search mechanism that permits them, to some degree, to distinguish between infected and uninfected hosts.
通过在噬菌蛭弧菌109菌株在大肠杆菌ML 35（lac i(-)z(+)y(-)）上进行单感染周期的过程中测量呼吸速率和邻硝基苯基-β-D-吡喃半乳糖苷水解速率，研究了噬菌蛭弧菌感染对宿主通透性和呼吸作用的影响。数据表明，寄生虫攻击宿主的早期后果包括宿主通透性增加和呼吸活性普遍受到破坏，并且表明这两种现象都源于宿主膜的早期损伤。周期开始后损伤迅速出现，以及链霉素未能阻止损伤，表明寄生虫完全穿透宿主并非观察到这些效应的必要条件。数据还表明，噬菌蛭弧菌生长不利用宿主的能量产生机制，并表明寄生虫可能有一种搜索机制，使它们在一定程度上能够区分受感染和未受感染的宿主。
