大肠杆菌K-12重组体模型系统中的选择性自细胞毒性
Selective autocytotoxicity in a model system of Escherichia coli K-12 recombinants.
作者信息
Martinez D, Whitehouse F
出版信息
J Bacteriol. 1973 May;114(2):882-4. doi: 10.1128/jb.114.2.882-884.1973.
Abstract
Autocytotoxicity was shown by Lac(+) recombinant strains of Escherichia coli K-12 when their growth was inhibited in media containing o-nitrophenyl-beta-d-galactopyranoside. Lac(-) strains without lactose permease or beta-galactosidase activity grew well. Selective autocytotoxicity was shown by simultaneous inhibition of Lac(+) cells and multiplication of Lac(-) cells grown together in this medium.
摘要
当大肠杆菌K-12的Lac(+)重组菌株在含有邻硝基苯基-β-D-吡喃半乳糖苷的培养基中生长受到抑制时，表现出自细胞毒性。没有乳糖通透酶或β-半乳糖苷酶活性的Lac(-)菌株生长良好。在这种培养基中共同生长时，对Lac(+)细胞的同时抑制和Lac(-)细胞的增殖表现出选择性自细胞毒性。
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