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一种新型青霉素衍生物巴卡西林的临床研究(作者译)

[Clinical investigation on a new penicillin derivative, bacampicillin (author's transl)].

作者信息

Nishio A, Kumamoto Y, Sakai S, Saka T, Terada M, Hikita M

出版信息

Jpn J Antibiot. 1979 Aug;32(8):839-45.

PMID:490899
Abstract

A clinical investigation was carried out on a new penicillin derivative, bacampicillin with the following results. (1) Clinical effect--Bacampicillin was administered orally to 18 patients with acute simple cystitis, acute simple pyelonephritis, chronic prostatitis and acute gonorrhoic urethritis. Daily doses ranged from 750 mg to 1,000 mg. The administration continued for 4 to 14 days. Clinical effect was excellent in 10 patients and good in 5 patients. (2) Side effect--Side effects were noticed in 4 patients, one was allergic eruption and other 3 were gastralgia. In a patient the drug was discontinued to administer.

摘要

对一种新型青霉素衍生物巴卡西林进行了一项临床研究,结果如下。(1)临床疗效——对18例急性单纯性膀胱炎、急性单纯性肾盂肾炎、慢性前列腺炎和急性淋菌性尿道炎患者口服巴卡西林。日剂量为750毫克至1000毫克。给药持续4至14天。10例患者临床疗效极佳,5例患者疗效良好。(2)副作用——4例患者出现副作用,1例为过敏性皮疹,其他3例为胃痛。有1例患者停止给药。

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