Sakaguchi H
Jpn J Antibiot. 1977 Jan;30(1):124-7.
Amoxicillin, a synthetic penicillin with a broad antibacterial spectrum, was administed in a daily dose of 1.0 g (in potency) to 47 patients who came to the department of urology (6 patients in whom the antibiotic was used for the prevention of infections included). The results are summarized in the following. 1. The patients with urological infections who were treated with amoxicillin included 20 patients with acute cystitis, 1 with acute urethritis, 18 with chronic prostatitis, 1 with epididymitis, 1 with pyelonephritis and 6 patients in whom the antibiotic was used for the prevention of infections. Amoxicillin was remarkably effective in 27 patients (58.7%), effective in 7 patients (15.2%), but ineffective in 12 patients (26.1%), with the overall effectiveness of 73.9%. The therapy was withdrawn in one patient because of side effects. 2. A patient with acute cystitis showed eruption which was probably associated with allergic reaction to penicillin, and the administration was discontinued. Other side effects worth mentioning were not observed.
阿莫西林是一种具有广谱抗菌作用的合成青霉素,对47名前来泌尿外科就诊的患者(其中包括6名使用该抗生素预防感染的患者)采用每日剂量1.0g(按效价计)给药。结果总结如下。1. 接受阿莫西林治疗的泌尿系统感染患者包括20例急性膀胱炎患者、1例急性尿道炎患者、18例慢性前列腺炎患者、1例附睾炎患者、1例肾盂肾炎患者以及6名使用该抗生素预防感染的患者。阿莫西林对27例患者(58.7%)疗效显著,对7例患者(15.2%)有效,但对12例患者(26.1%)无效,总体有效率为73.9%。有1例患者因出现副作用而停药。2. 1例急性膀胱炎患者出现皮疹,可能与对青霉素过敏反应有关,遂停药。未观察到其他值得提及的副作用。