Sato H, Mayuzumi T
Jpn J Antibiot. 1976 Jan;29(1):4-6.
Amoxicillin (AMPC), an oral preparation of broad spectrum synthetic penicillin, was used for treatment of 10 cases with urological infection, and the following results were obtained. 1. AMPC at a daily dose of 750 approximately 1,500 mg was administered for 7 approximately 49 days to 5 cases of acute cystitis, 2 cases of acute epididymitis and one case each of calculous hydronephrosis, chronic prostatitis and postoperative cystitis. As the result, AMPC was found remarkably effective in 2 cases, effective in 7 cases and ineffective in one case; that is, the effective rate was 9/10 (90.0%). 2. Total 8 strains of bacteria, comprising 5 strains of Escherichia coli and one strain each of Klebsiella, Staphylococcus epidermidis and Pseudomonas, were isolated from the urine. These bacteria were relatively responsive to AMPC as well as to ABPC. 3. The side effect possibly due to AMPC was slight gastro-intestinal disorder only in 2 of 10 cases. No other side effect was observed.
阿莫西林(AMPC)是一种广谱合成青霉素口服制剂,用于治疗10例泌尿系统感染患者,获得以下结果。1. 5例急性膀胱炎、2例急性附睾炎、1例结石性肾积水、1例慢性前列腺炎和1例术后膀胱炎患者,给予AMPC每日剂量约750至1500毫克,用药7至49天。结果显示,2例显效,7例有效,1例无效;有效率为9/10(90.0%)。2. 从尿液中分离出总共8株细菌,其中包括5株大肠杆菌、1株克雷伯菌、1株表皮葡萄球菌和1株假单胞菌。这些细菌对AMPC和ABPC均有较好反应。3. 10例患者中仅2例可能因AMPC出现轻微胃肠道紊乱副作用,未观察到其他副作用。