Ozaki T
Jpn J Physiol. 1979;29(2):195-209. doi: 10.2170/jjphysiol.29.195.
The effects of repetitive electrical stimulation of a node of Auerbach's plexus on both longitudinal and circular muscles were investigated by simultaneous recording of both muscle contractions. L-formed muscle strips, longitudinal and circular muscle strips, were made from a segment of rabbit small intestine. One strip was cut along, another strip was cut at 90 degrees to the oral-anal axis. The longitudinal muscle strip was peeled and Auerbach's plexus was exposed. Under a stereodissecting microscope the stimulating electrode, with tip diameter of 5--10 micron, was placed on a node of Auerbach's plexus situated at the junction of both muscle strips. Repetitive electrical stimulation of a node produced a mainly excitatory effect on spontaneous contractions of an orally-directed longitudinal muscle strip, excitatory and inhibitory effects on an anally-directed longitudinal muscle strip and a mostly excitatory effect on a circular muscle strip which always appeared with a delay after that on the longitudinal muscle. In a few instances the inhibitory effect of nodal stimulation was observed on the circular muscle. The evoked excitatory effect of longitudinal muscle was mainly due to a cholinergic mechanism, while that of circular muscle was partially due to cholinergic and partially noncholinergic activity. The evoked inhibition was nonadrenergic.
通过同时记录肌肉收缩情况，研究了反复电刺激奥厄巴赫神经丛的一个节段对纵肌和环肌的影响。从兔小肠的一段制作了L形肌条、纵肌条和环肌条。一条肌条沿纵向切割，另一条肌条与口-肛轴成90度角切割。将纵肌条剥离，暴露奥厄巴赫神经丛。在体视显微镜下，将尖端直径为5-10微米的刺激电极置于位于两条肌条交界处的奥厄巴赫神经丛的一个节段上。反复电刺激一个节段对向口侧的纵肌条的自发收缩主要产生兴奋作用，对向肛侧的纵肌条产生兴奋和抑制作用，对环肌条主要产生兴奋作用，且总是在纵肌条兴奋后延迟出现。在少数情况下，观察到节段刺激对环肌有抑制作用。纵肌的诱发兴奋作用主要归因于胆碱能机制，而环肌的诱发兴奋作用部分归因于胆碱能活性，部分归因于非胆碱能活性。诱发的抑制作用是非肾上腺素能的。
