Vinogradov A V, Zhuravleva I A, Lobanov N A, Movshovich B L
Kardiologiia. 1979 Aug;19(8):58-62.
Serial tests for the activity of creatine phosphokinase (CPK), specific cardiac isoenzyme MB CPK, lactic dehydrogenase (LDH) and its fractions LDH1 and LDH2 were conducted in 55 patients with myocardial infarction. The control group consisted of 15 healthy persons. It was found that an increase in total CPK activity allows the diagnosis of myocardial infarction to be confirmed in the first hours after the onset of the disease, while simultaneous increase in the activity of MB CPK makes the diagnosis authentic, which is particularly valuable in cases with an atypical course of the disease. A recurrent course of myocardial infarction is attended with parallel changes in the activity of total CPK and its MV fraction. Increased total CPK activity may be due both to myocardial infarction and to extracardiac causes.
对55例心肌梗死患者进行了肌酸磷酸激酶（CPK）、特异性心肌同工酶MB CPK、乳酸脱氢酶（LDH）及其同工酶LDH1和LDH2活性的系列检测。对照组由15名健康人组成。结果发现，总CPK活性升高可在疾病发作后的最初几小时内确诊心肌梗死，而MB CPK活性同时升高则使诊断更可靠，这在疾病病程不典型的情况下尤为重要。心肌梗死复发时，总CPK及其MB同工酶活性会平行变化。总CPK活性升高可能是由心肌梗死和心外原因引起的。
