[Atypical creatine phosphokinase isoenzyme fraction in the diagnosis of acute myocardial infarction].

A study of CPK isoenzyme spectrum in acute myocardial infarction, using electrophoresis and isoelectric focusing techniques, demonstrated the possibility of an earlier detection of myocardial necrosis on the basis of changes in CPK MM subzones, rather than the CPK MB test. This approach does not increase the specificity of isoenzyme CPK assays, but improves the reliability of biochemical assessment of the time of onset and depth of myocardial affection.