[酶学检测在评估急性心肌梗死疾病严重程度及预后中的价值]
[Value of the enzyme tests in the evaluation of the severity of disease and prognosis in acute myocardial infarct].
作者信息
Bart B Ia, Pivovarov V A
出版信息
Kardiologiia. 1979 Aug;19(8):91-5.
The article discusses the results of simultaneous tests for the activity of total lactate dehydrogenase (LDH), its isoenzymes and creatine phosphokinase (CPK) in blood serum of 450 patients with macrofocal myocardial infarction; in 213 of them the disease followed a severe course and in 237 a mild course. The activity of these enzymes was used in this group of patients for judging the immediate and in 190 patients wht late prognosis. The authors' study showed that the maximum indices of the activity of LDH, LDH1 fraction and CPK in blood serum were higher in patients with severe myocardial infarction than in those with a mild course of the disease. The immediate and late prognosis in myocardial infarction was graver in higher activity of serum enzymes.
本文讨论了对450例大片心肌梗死患者血清中总乳酸脱氢酶（LDH）及其同工酶和肌酸磷酸激酶（CPK）活性进行同步检测的结果；其中213例病情严重，237例病情较轻。在这组患者中，这些酶的活性被用于判断近期预后，在190例患者中用于判断远期预后。作者的研究表明，重症心肌梗死患者血清中LDH、LDH1组分和CPK活性的最高指标高于轻症患者。血清酶活性越高，心肌梗死的近期和远期预后越差。
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