人类恶性黑色素瘤中经辐射的肿瘤细胞自身免疫作用
Autoimmunization with irradiated tumour cells in human malignant melanoma.
作者信息
Ikonopisov R L, Lewis M G, Hunter-Craig I D, Bodenham D C, Phillips T M, Cooling C I, Proctor J, Fairley G H, Alexander P
出版信息
Br Med J. 1970 Jun 27;2(5712):752-4. doi: 10.1136/bmj.2.5712.752.
Abstract
Thirteen patients have been immunized with their own irradiated melanoma cells on one or more occasions. Following these autografts tumour-specific cytotoxic antibodies were produced, the longest response lasting 14 days. This procedure had no apparent effect on the course of the disease in these patients.
摘要
13名患者已接受过一次或多次自身照射过的黑色素瘤细胞免疫。这些自体移植后产生了肿瘤特异性细胞毒性抗体，最长反应持续14天。该程序对这些患者的病程没有明显影响。
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