Fletcher J, Goldstein E
Br J Exp Pathol. 1970 Jun;51(3):280-5.
The effect of parenteral iron preparations on experimental pyelonephritis has been investigated using animals primed by intravenous inoculation of various bacteria. Injection of small molecular weight iron complexes allowed growth of bacteria with the development of frank renal abscesses. Large molecular weight complexes, which do not pass the glomerulus, did not cause renal infection.
通过给动物静脉接种各种细菌进行致敏,研究了胃肠外铁制剂对实验性肾盂肾炎的影响。注射小分子量铁复合物会使细菌生长,并形成明显的肾脓肿。而不能通过肾小球的大分子量复合物则不会引发肾脏感染。