Fletcher J
Immunology. 1971 Apr;20(4):493-500.
Iron in excess of the binding capacity of transferrin allows to grow in fresh serum. This appears to be due to two mechanisms. Firstly iron stimulates growth as it is an essential metabolite which is not available to in serum. Secondly, it interferes with bacterial killing, a process normally mediated by natural antibody and complement.
超过转铁蛋白结合能力的铁会在新鲜血清中促进其生长。这似乎是由于两种机制。首先,铁作为一种血清中无法获得的必需代谢物,会刺激生长。其次,它会干扰细菌杀灭过程,而这一过程通常由天然抗体和补体介导。