Evans B A, Catterall R D
Br Med J. 1970 May 9;2(5705):335-6. doi: 10.1136/bmj.2.5705.335.
Nifuratel (Magmilor) was compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis by a randomized double-blind trial. Only 18 out of 47 patients (38%) treated with nifuratel were found to be cured, whereas 42 out of 49 patients (85%) treated with metronidazole were cured. Severe reactions, necessitating withdrawal of treatment, occurred in three patients treated with nifuratel. There were no serious side-effects with metronidazole. The results of this trial indicate that nifuratel is not a satisfactory substitute for metronidazole in the treatment of trichomoniasis.
通过一项随机双盲试验，比较了硝呋太尔（麦咪诺）与甲硝唑（灭滴灵）治疗滴虫性阴道炎的效果。接受硝呋太尔治疗的47例患者中，仅18例（38%）被治愈，而接受甲硝唑治疗的49例患者中有42例（85%）被治愈。接受硝呋太尔治疗的3例患者出现严重反应，需要停止治疗。甲硝唑没有严重的副作用。该试验结果表明，在治疗滴虫病方面，硝呋太尔不是甲硝唑的令人满意的替代药物。
