控制大肠杆菌K-12中L-谷氨酸脱羧酶合成的基因。
Gene controlling L-glutamic acid decarboxylase synthesis in Escherichia coli K-12.
作者信息
Lupo M, Halpern Y S
出版信息
J Bacteriol. 1970 Aug;103(2):382-6. doi: 10.1128/jb.103.2.382-386.1970.
Abstract
Genetically related Escherichia coli K-12 strains were found to differ widely in their l-glutamic acid decarboxylase (GAD) activity. This variation is due to differences in the amount of GAD produced by the different cultures, rather than to the appearance of altered enzymes differing in catalytic activity. A regulatory gene, gadR, which controls the amount of GAD was mapped on the E. coli K-12 chromosome. A strain with a lesion in the structural gene for GAD is described.
摘要
人们发现，基因相关的大肠杆菌K-12菌株在其L-谷氨酸脱羧酶（GAD）活性上存在很大差异。这种差异是由于不同培养物产生的GAD量不同，而不是由于出现了催化活性不同的变异酶。一个控制GAD量的调控基因gadR被定位在大肠杆菌K-12染色体上。本文描述了一株GAD结构基因有损伤的菌株。
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