噬菌体φX174的感染过程。8. 关于必需细菌“位点”的证据。
The process of infection with bacteriophage phiX174. 8. Evidence for an essential bacterial "site".
作者信息
Yarus M J, Sinsheimer R L
出版信息
J Virol. 1967 Feb;1(1):135-44. doi: 10.1128/JVI.1.1.135-144.1967.
Abstract
The burst of a starved bacterium infected with several øX174 bacteriophage was usually found to contain genetic traits of only one of the possible parents; less often, two phage multiplied in the same host cell. Unstarved cells, in contrast, supported the growth of at least four parental phage types. The unproductive phage seemed to be able to undergo the intracellular transition from parental single-stranded deoxyribonucleic acid to the double-stranded "replicative form" (RF). These results are taken to mean that some bacterial factor required for a step between RF synthesis and maturation of progeny is limited in starved cells.
摘要
通常发现，被几种øX174噬菌体感染的饥饿细菌的裂解物中，往往只含有一种可能亲本的遗传特性；较少见的情况是，两种噬菌体在同一宿主细胞中增殖。相比之下，未饥饿的细胞能支持至少四种亲本噬菌体类型的生长。无繁殖能力的噬菌体似乎能够在细胞内从亲本单链脱氧核糖核酸转变为双链“复制型”（RF）。这些结果意味着，在RF合成与子代成熟之间的某个步骤所需的某种细菌因子在饥饿细胞中是有限的。
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