补体第六成分在肾异种移植排斥反应中的作用。
The role of the sixth component of complement in the rejection of kidney xenografts.
作者信息
Mejía-Laguna J E, García-Cornejo M, Lopez-Soriano F, Biro C E
出版信息
Immunology. 1970 Nov;19(5):767-9.
Abstract
The time of rejection of dog kidney grafts in normal and in C6-deficient rabbits was not significantly different. It is concluded that the last four components of complement are not involved in this form of violent xenograft rejection. The requirement for the first components may be explained by polymorphonuclear leucocyte chemotaxis, since these cells were found in the glomeruli of rejected kidneys.
摘要
正常兔和C6缺陷兔体内犬肾移植的排斥时间无显著差异。由此得出结论，补体的最后四个成分不参与这种剧烈的异种移植排斥反应。对补体第一成分的需求可能是由多形核白细胞趋化作用来解释的，因为在被排斥肾脏的肾小球中发现了这些细胞。
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