O'Regan C C, Robitaille P, Pinto-Blonde M, Chartrand C
Immunology. 1979 Oct;38(2):245-8.
Puppy hearts were engrafted to C6-deficient rabbits, and also to complement-sufficient animals in order to determine the influence of the sixth component of complement on xenograft rejection. Delayed rejection was observed in the puppy hearts engrafted to the C6-deficient animals indicating that complement sufficiency of C6 is required for hyperacute xenograft rejection.
将幼犬心脏移植到C6缺陷型兔体内,同时也移植到补体充足的动物体内,以确定补体第六成分对异种移植排斥反应的影响。在移植到C6缺陷型动物体内的幼犬心脏中观察到延迟排斥反应,这表明超急性异种移植排斥反应需要C6补体充足。