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肾异种移植在白细胞减少兔中的长期存活

Prolonged survival of kidney xenografts in leucopenic rabbits.

作者信息

Mejía-Laguna J E, Martínez-Palomo A, López-Soriano F, García-Cornjeo M, Biro C E

出版信息

Immunology. 1971 Dec;21(6):879-82.

PMID:4943145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1408272/
Abstract

Rabbits rendered leucopenic by means of nitrogen mustard reject kidney xenografts more slowly than normal controls It is therefore probable that polymorphonuclear leucocytes play an important role in the acute rejection of xenografts. The previously reported complement requirement for xenograft rejection was also confirmed in this work, by depleting the graft recipients of C3 with cobra venom factor.

摘要

用氮芥使家兔出现白细胞减少后，其对肾异种移植的排斥比正常对照组更为缓慢。因此，多形核白细胞很可能在异种移植的急性排斥中起重要作用。在这项研究中，通过用眼镜蛇毒因子使移植受体的C3耗竭，也证实了先前报道的异种移植排斥对补体的需求。

相似文献

1
Prolonged survival of kidney xenografts in leucopenic rabbits.肾异种移植在白细胞减少兔中的长期存活
Immunology. 1971 Dec;21(6):879-82.
2
Prolongation of renal xenografts by complement suppression.通过补体抑制延长肾异种移植的存活时间。
Surg Forum. 1966;17:478-80.
3
The role of the sixth component of complement in the rejection of kidney xenografts.补体第六成分在肾异种移植排斥反应中的作用。
Immunology. 1970 Nov;19(5):767-9.
4
Morphologic study of the participation of the complement system in hyperacute rejection of renal xenotransplants.补体系统参与肾异种移植超急性排斥反应的形态学研究。
Am J Pathol. 1972 Oct;69(1):71-8.
5
Studies on the mechanism of canine renal allograft rejection.犬肾同种异体移植排斥反应机制的研究。
Transplant Proc. 1969 Mar;1(1):296-300.
6
Prolongation of renal xenografts by the simultaneous sequestration of preformed antibody, inhibition of complement, coagulation and antibody synthesis.通过同时隔离预先形成的抗体、抑制补体、凝血和抗体合成来延长肾异种移植的存活时间。
Transplant Proc. 1971 Mar;3(1):538-41.
7
The effect of modification of coagulation factors on xenograft rejection.凝血因子修饰对异种移植排斥反应的影响。
Surg Forum. 1971;22:242-4.
8
Prolongation of heterograft survival by electrophoretic extraction of preformed antibody.通过电泳提取预先形成的抗体延长异种移植物存活时间。
Surg Forum. 1970;21:263-5.
9
Delay of the heterograft reaction by selective plasmapharesis.通过选择性血浆置换延迟异种移植反应。
Surg Forum. 1970;21:261-3.
10
The effect of rabbit anti-platelet anti-serum on the rejection of the pig and rabbit kidney by the dog.兔抗血小板抗血清对犬排斥猪和兔肾脏的影响。
Trans Am Soc Artif Intern Organs. 1971;17:60-3.

引用本文的文献

1
Human leukocytes regulate ganglioside expression in cultured micro-pig aortic endothelial cells.人类白细胞调节培养的微型猪主动脉内皮细胞中的神经节苷脂表达。
Lab Anim Res. 2012 Dec;28(4):255-63. doi: 10.5625/lar.2012.28.4.255. Epub 2012 Dec 26.
2
The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients.α1,3-半乳糖基转移酶基因敲除异种移植受体中的天然免疫反应与凝血激活
Transplantation. 2009 Mar 27;87(6):805-12. doi: 10.1097/TP.0b013e318199c34f.
3
Activation of naive xenogeneic but not allogeneic endothelial cells by human naive neutrophils: a potential occult barrier to xenotransplantation.人天然中性粒细胞激活天然异种而非同种异体内皮细胞：异种移植的潜在隐匿屏障。
Am J Pathol. 1997 Jul;151(1):111-20.
4
Morphologic study of the participation of the complement system in hyperacute rejection of renal xenotransplants.补体系统参与肾异种移植超急性排斥反应的形态学研究。
Am J Pathol. 1972 Oct;69(1):71-8.
5
Delayed rejection of cardiac xenografts in C6-deficient rabbits.C6缺陷兔心脏异种移植的延迟排斥反应。
Immunology. 1979 Oct;38(2):245-8.

本文引用的文献

1
A new concept of immunosuppression in hypersensitivity reactions and in transplantation immunity.超敏反应和移植免疫中免疫抑制的新概念。
Surv Ophthalmol. 1966 Aug;11(4):498-505.
2
Isolation of a fragment (C3a) of the third component of human complement containing anaphylatoxin and chemotactic activity and description of an anaphylatoxin inactivator of human serum.分离出含有过敏毒素和趋化活性的人补体第三成分的一个片段（C3a），并描述一种人血清过敏毒素灭活剂。
J Exp Med. 1969 May 1;129(5):1109-30. doi: 10.1084/jem.129.5.1109.
3
C5 chemotactic fragments produced by an enzyme in lysosomal granules of neutrophils.由中性粒细胞溶酶体颗粒中的一种酶产生的C5趋化片段。
J Immunol. 1970 Mar;104(3):535-43.
4
Immunologic studies in human organ transplantation. IV. Serologic and pathologic studies following heterotransplantation of the kidney.人体器官移植中的免疫学研究。IV. 肾脏异种移植后的血清学和病理学研究。
Am J Pathol. 1967 Apr;50(4):605-22.
5
The role of the sixth component of complement in the rejection of kidney xenografts.补体第六成分在肾异种移植排斥反应中的作用。
Immunology. 1970 Nov;19(5):767-9.
6
The glomerulus in man one hour after transplantation. An electron microscopic study.移植后一小时人体肾小球的电子显微镜研究
Am J Pathol. 1970 Jan;58(1):85-104.
7
A specific inactivator of mammalian C'4 isolated from nurse shark (Ginglymostoma cirratum) serum.一种从护士鲨（Ginglymostoma cirratum）血清中分离出的哺乳动物补体C4特异性灭活剂。
J Exp Med. 1969 Aug 1;130(2):217-41. doi: 10.1084/jem.130.2.217.
8
Renal xenograft prolongation by suppression of natural antibody.通过抑制天然抗体延长肾异种移植存活时间
J Surg Res. 1968 May;8(5):211-3. doi: 10.1016/0022-4804(68)90088-7.