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[脊髓隐球菌性肉芽肿性蛛网膜炎——病例报告(作者译)]

[Cryptococcal granulomatous arachnitis of the spinal cord--a case report (author's transl)].

作者信息

Niizuma H, Higuchi H, Tajima T

出版信息

No Shinkei Geka. 1979 Aug;7(8):805-8.

PMID:492461
Abstract

A case of cryptococcal granulomatous arachnitis of the spinal cord was reported. A 12-year-old boy suffered from sudden occipitalgia and left hemiparesis. The symptoms disappeared spontaneously in about a half year. The next year, he consulted an orthopedist because of lumbago and gait disturbance. Myelography through the cisternal route showed complete block at the level of L1. Exploratory laminectomy of D12 and L1 revealed adhesive arachnitis. Symptoms were improved immediately after the operation. At the age of 15, he was admitted to our clinic, because of sudden onset of headache and vomiting. Computed tomography showed marked hydrocephalus. He recovered by ventriculoperitoneal shunt, and was discharged. The next year, sudden back pain occurred. Gait disturbance, sensory disturbance of the legs and trunks below the mamilla, and dysuria appeared gradually. He was readmitted and laminectomy of D2-4 was performed. The arachnoid membrane was white and 2 mm in thickness diffusely. Thickened arachnoid membrane was removed at the level of D2-4. Histological diagnosis was granulomatous arachnitis. Cryptococcus was seen in the removed tissue. Symptoms were improved after operation. One thousand milligrams of amphoterisin B was injected intermittently. He was discharged on food. Spinal symptoms in cryptococcosis are rare. Operative procedures were effective before the administration of amphoterisin B.

摘要

报告了1例脊髓隐球菌性肉芽肿性蛛网膜炎病例。一名12岁男孩突发枕部疼痛和左侧偏瘫。症状在大约半年后自行消失。次年,他因腰痛和步态障碍咨询了骨科医生。经脑池途径的脊髓造影显示L1水平完全梗阻。D12和L1的探查性椎板切除术显示粘连性蛛网膜炎。术后症状立即改善。15岁时,他因突然头痛和呕吐入住我院。计算机断层扫描显示明显脑积水。他通过脑室腹腔分流术康复并出院。次年,突发背痛。步态障碍、乳头以下腿部和躯干感觉障碍以及排尿困难逐渐出现。他再次入院,行D2 - 4椎板切除术。蛛网膜呈白色,弥漫性增厚2毫米。在D2 - 4水平切除增厚的蛛网膜。组织学诊断为肉芽肿性蛛网膜炎。在切除组织中发现隐球菌。术后症状改善。间歇性注射1000毫克两性霉素B。他出院时情况良好。隐球菌病的脊髓症状罕见。在使用两性霉素B之前,手术治疗有效。

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