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Induction of immunological tolerance by a hapten (DNP) bound to a non-immunogenic protein carrier.

作者信息

Borel Y

出版信息

Nat New Biol. 1971 Apr 7;230(14):180-2. doi: 10.1038/newbio230180a0.

DOI:10.1038/newbio230180a0
PMID:4928923
Abstract
摘要

相似文献

1
Induction of immunological tolerance by a hapten (DNP) bound to a non-immunogenic protein carrier.通过与非免疫原性蛋白质载体结合的半抗原(二硝基苯酚)诱导免疫耐受。
Nat New Biol. 1971 Apr 7;230(14):180-2. doi: 10.1038/newbio230180a0.
2
Induction of anti-hapten antibody response by hapten-isologous carrier conjugate. II. Specificity of hapten-reactive helper T cells.半抗原-同种异体载体偶联物诱导抗半抗原抗体反应。II. 半抗原反应性辅助性T细胞的特异性
Cell Immunol. 1975 Aug;18(2):396-410. doi: 10.1016/0008-8749(75)90068-4.
3
The influence of epitope density on the immunological properties of hapten-protein conjugates. III. Induction of hapten-specific tolerance by heavily and lightly hapten-substituted serum albumin.表位密度对半抗原-蛋白质缀合物免疫特性的影响。III. 高度和低度半抗原取代的血清白蛋白诱导半抗原特异性耐受性
Scand J Immunol. 1974;3(6):797-808. doi: 10.1111/j.1365-3083.1974.tb01315.x.
4
Deletion of hapten-binding cells by a highly radioactive 125-I conjugate.用高放射性的125-I缀合物清除半抗原结合细胞。
J Exp Med. 1972 Aug 1;136(2):305-17. doi: 10.1084/jem.136.2.305.
5
In vitro initiated secondary anti-hapten response. 3. Separable roles of hapten and carrier in immune paralysis.体外引发的二次抗半抗原反应。3. 半抗原和载体在免疫麻痹中的可分离作用。
Immunochemistry. 1972 May;9(5):491-504. doi: 10.1016/0019-2791(72)90059-6.
6
Effect on tolerance induction of the mode of attachment of the hapten the carrier.半抗原与载体的连接方式对耐受性诱导的影响。
J Immunol. 1975 Nov;115(5):1409-13.
7
Induction of primary and inhibition of secondary antibody response to hapten by hapten conjugates of type III pneumococcal polysaccharide.III型肺炎球菌多糖半抗原结合物对半抗原的初次抗体应答的诱导及二次抗体应答的抑制作用
Cell Immunol. 1975 Feb;15(2):321-35. doi: 10.1016/0008-8749(75)90011-8.
8
Regulatory functions of hapten-reactive helper and suppressor T lymphocytes. I. Detection and characterization of hapten-reactive suppressor T-cell activity in mice immunized with hapten-isologous protein conjugate.半抗原反应性辅助性和抑制性T淋巴细胞的调节功能。I. 用半抗原-同源蛋白偶联物免疫的小鼠中半抗原反应性抑制性T细胞活性的检测与特性分析。
J Exp Med. 1977 Jul 1;146(1):74-90. doi: 10.1084/jem.146.1.74.
9
Carrier-determined tolerance in various strains of mice: the role of isogenic IgG in the induction of hapten specific tolerance.
Proc Soc Exp Biol Med. 1974 Feb;145(2):470-4. doi: 10.3181/00379727-145-37833.
10
Immunological tolerance in bone marrow-derived lymphocytes. I. Evidence for an intracellular mechanism of inactivation of hapten-specific precursors of antibody-forming cells.骨髓源性淋巴细胞中的免疫耐受性。I. 抗体形成细胞的半抗原特异性前体细胞失活的细胞内机制的证据。
J Exp Med. 1972 Dec 1;136(6):1404-29. doi: 10.1084/jem.136.6.1404.

引用本文的文献

1
Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies.凝血因子 VIII:免疫原性和免疫耐受策略的观点。
Front Immunol. 2020 Jan 17;10:3078. doi: 10.3389/fimmu.2019.03078. eCollection 2019.
2
Tolerating Factor VIII: Recent Progress.耐受因子 VIII:最新进展。
Front Immunol. 2020 Jan 10;10:2991. doi: 10.3389/fimmu.2019.02991. eCollection 2019.
3
Recombinant factor VIII Fc fusion protein drives regulatory macrophage polarization.重组因子 VIII Fc 融合蛋白驱动调节性巨噬细胞极化。
Blood Adv. 2018 Nov 13;2(21):2904-2916. doi: 10.1182/bloodadvances.2018024497.
4
Tolerogenic properties of the Fc portion of IgG and its relevance to the treatment and management of hemophilia.IgG Fc 段的免疫耐受特性及其与血友病治疗和管理的相关性。
Blood. 2018 May 17;131(20):2205-2214. doi: 10.1182/blood-2017-12-822908. Epub 2018 Mar 27.
5
Many factor VIII products available in the treatment of hemophilia A: an embarrassment of riches?治疗甲型血友病有多种凝血因子VIII产品可供选择:产品过多是好事还是坏事?
J Blood Med. 2017 Jun 15;8:67-73. doi: 10.2147/JBM.S103796. eCollection 2017.
6
Induction of tolerance by administration of hapten-immunoglobulin conjugates is associated with decreased IL-2 and IL-4 production.通过给予半抗原-免疫球蛋白缀合物诱导耐受与白细胞介素-2和白细胞介素-4产生减少有关。
Arch Dermatol Res. 1995;287(2):123-8. doi: 10.1007/BF01262319.
7
From nonspecific to specific immunosuppression: facts and speculation.从非特异性免疫抑制到特异性免疫抑制:事实与推测
Springer Semin Immunopathol. 1984;7(1):19-24. doi: 10.1007/BF01891776.
8
Suppressor T cell memory. II. The role of memory suppressor T cells in tolerance to human gamma globulin.抑制性T细胞记忆。II. 记忆性抑制性T细胞在对人丙种球蛋白耐受性中的作用。
J Exp Med. 1983 Mar 1;157(3):957-73. doi: 10.1084/jem.157.3.957.
9
Induction of immunity and tolerance in vitro by hapten protein conjugates. I. The relationship between the degree of hapten conjugation and the immunogenicity of dinitrophenylated polymerized flagellin.半抗原蛋白偶联物在体外诱导免疫和耐受。I. 二硝基苯基化聚合鞭毛蛋白的半抗原偶联程度与免疫原性之间的关系。
J Exp Med. 1972 Apr 1;135(4):735-53. doi: 10.1084/jem.135.4.735.
10
Nonantigenicity and immunologic tolerance: the role of the carrier in the induction of tolerance to the hapten.非抗原性与免疫耐受性:载体在诱导对半抗原的耐受性中的作用。
J Exp Med. 1971 Oct 1;134(4):1046-61. doi: 10.1084/jem.134.4.1046.