Dupont B, Charmot G, Lapresle C
Nouv Presse Med. 1979 Apr 28;8(19):1579-81.
In a 26-year-old man who had spent time in a trypanosome endemic zone, lesions of erythema marginatum progressing by acute exacerbations for 2 years despite various forms of treatment led to the discovery of a multiple lymphadenopathy and a greatly accelerated sedimentation rate. These findings suggested a diagnosis which was confirmed by the discovery of Trypanosoma gambiense in the blood and lymph node aspirate. In addition, there was an albumino-lymphocytic reaction in the cerebrospinal fluid. Finally, an atrioventricular block was discovered. All these symptoms and signs responsed to treatment with melarsoprol but a pericardial reaction developed, possibly of immunoallergic origin.
一名26岁男子曾在锥虫病流行区生活过，尽管接受了各种形式的治疗，但边缘性红斑病变急性加重持续了2年，这导致发现多处淋巴结病和血沉大幅加快。这些发现提示了一种诊断，血液和淋巴结穿刺液中发现冈比亚锥虫证实了这一诊断。此外，脑脊液中存在白蛋白-淋巴细胞反应。最后，发现了房室传导阻滞。所有这些症状和体征对美拉胂醇治疗均有反应，但出现了心包反应，可能源于免疫过敏。
