派尔集合淋巴结：家兔中产生IgA免疫细胞前体的丰富来源。
Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit.
作者信息
Craig S W, Cebra J J
出版信息
J Exp Med. 1971 Jul 1;134(1):188-200. doi: 10.1084/jem.134.1.188.
Abstract
The proliferative and differentiative potential of Peyer's patch, peripheral blood, and popliteal lymph node cells was assessed by allogeneic cell transfer followed by quantitation of donor immunocytes by immunofluorescence. It was found that Peyer's patches are a highly enriched source of cells which have the potential to proliferate and differentiate into IgA-producing immunocytes and that the Peyer's patch cells are far more efficient in seeding the gut of irradiated recipient rabbits with donor cells that give rise to immunoglobulin-producing cells than cells from peripheral blood or popliteal lymph nodes.
摘要
通过异体细胞转移，随后用免疫荧光法定量供体免疫细胞，评估派尔集合淋巴结、外周血和腘淋巴结细胞的增殖和分化潜能。研究发现，派尔集合淋巴结是细胞的高度富集来源，这些细胞有增殖并分化为产生IgA的免疫细胞的潜能，并且与外周血或腘淋巴结的细胞相比，派尔集合淋巴结细胞在将产生免疫球蛋白的供体细胞植入受辐照受体兔肠道方面效率要高得多。
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J Exp Med. 1971 Jul 1;134(1):188-200. doi: 10.1084/jem.134.1.188.
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