Roux J J, Deveze J L, Escojido H, Ohresser P
Respiration. 1979;38(1):43-9. doi: 10.1159/000194057.
13 patients with chronic obstructive pulmonary disease (COPD) were studied for left ventricular function immediately after acute decompensation. Parameters of right and left ventricular function were measured. Mean pulmonary wedge pressure (Paw) was elevated (11.9 mm Hg) but there was no correlation between Paw and left ventricular end-diastolic pressure (LVEDP). The indices of left ventricular contractility were in the normal range. In 4 patients, LVEDP was too high. A correlation was established between RVEDP and LVEDP. Left ventricular compliance, as studied by the index of Diamond and Forrester, was abnormal. Two conclusions are discussed: (1) in COPD, Paw cannot indicate left ventricular dysfunction; (2) alteration of left ventricular compliance is possibly related to an elevation of RVEDP.
对13例慢性阻塞性肺疾病(COPD)患者在急性失代偿后立即进行左心室功能研究。测量了右心室和左心室功能参数。平均肺楔压(Paw)升高(11.9毫米汞柱),但Paw与左心室舒张末期压力(LVEDP)之间无相关性。左心室收缩性指标在正常范围内。4例患者的LVEDP过高。右心室舒张末期压力(RVEDP)与LVEDP之间建立了相关性。通过Diamond和Forrester指数研究的左心室顺应性异常。讨论了两个结论:(1)在COPD中,Paw不能表明左心室功能障碍;(2)左心室顺应性改变可能与RVEDP升高有关。