Murphy M J, Culliford E J, Parsons V
Resuscitation. 1979;7(1):35-44. doi: 10.1016/0300-9572(79)90013-3.
A male patient was admitted to hospital 12 h after self-poisoning with mercuric chloride. He suffered multiple complications including acute renal failure, ulcerative colitis, anaemia, disseminated intravascular coagulation, chronic sepsis and severe weight loss. Initially he responded well to resuscitative measures and intensive supportive therapy, which included ventilation of the lungs, haemodialysis, dimercaprol, antibiotics, parenteral feeding and gastrointestinal surgery. Unfortunately the sepsis was never satisfactorily eradicated despite satisfactory serum concentrations of the appropriate antibiotics. On day 43 after poisoning he had a grand mal fit; after this there were focal neurological signs and on lumbar puncture he was found to have a raised protein concentration and raised pressure in his cerebrospinal fluid. The condition of the patient rapidly deteriorated and on day 47 he died. Post-mortem examination revealed a large cerebellar abscess. The literature on mercury poisoning is reviewed.
一名男性患者在自服氯化汞12小时后入院。他出现了多种并发症，包括急性肾衰竭、溃疡性结肠炎、贫血、弥散性血管内凝血、慢性败血症和严重体重减轻。最初，他对复苏措施和强化支持治疗反应良好，这些治疗包括肺部通气、血液透析、二巯丙醇、抗生素、肠外营养和胃肠手术。不幸的是，尽管适当抗生素的血清浓度令人满意，但败血症从未得到令人满意的根除。中毒后第43天，他发生了一次癫痫大发作；此后出现了局灶性神经体征，腰椎穿刺发现他脑脊液中的蛋白质浓度升高和压力升高。患者病情迅速恶化，于第47天死亡。尸检发现一个巨大的小脑脓肿。本文对汞中毒的文献进行了综述。
