巴氯芬治疗痉挛
Baclofen in the treatment of spasticity.
作者信息
Hudgson P, Weightman D
出版信息
Br Med J. 1971 Oct 2;4(5778):15-7. doi: 10.1136/bmj.4.5778.15.
Abstract
Baclofendagger (Lioresal), a derivative of gamma-aminobutyric acid, was introduced in 1966 as a possible treatment for spasticity due to corticospinal tract lesions. Preliminary studies suggested that it may be more effective than other spasmolytic agents currently available, and a double-blind controlled trial in a group of 23 patients against placebo has shown it to be significantly more effective.
摘要
巴氯芬（力奥来素），一种γ-氨基丁酸衍生物，于1966年被引入，作为治疗因皮质脊髓束损伤引起的痉挛的一种可能疗法。初步研究表明，它可能比目前可用的其他解痉药更有效，一项针对23名患者与安慰剂对照的双盲试验表明它明显更有效。
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