Krisch H M, Shah D B, Berger H
J Virol. 1971 Apr;7(4):491-8. doi: 10.1128/JVI.7.4.491-498.1971.
Deoxyribonucleic acid replication and genetic recombination were investigated after infection of Escherichia coli with ligase-deficient rII bacteriophage T4D. The major observations are: (i) deoxyribonucleic acid synthesis is discontinuous, (ii) the discontinuities are more slowly repaired than in wild-type infection, (iii) host ligase is required for viability, and (iv) genetic recombination is increased.
在用连接酶缺陷型的rII噬菌体T4D感染大肠杆菌后,对脱氧核糖核酸复制和基因重组进行了研究。主要观察结果如下:(i)脱氧核糖核酸合成是不连续的,(ii)与野生型感染相比,这些不连续处的修复更慢,(iii)宿主连接酶对于存活是必需的,以及(iv)基因重组增加。