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卵巢黏液性囊腺瘤的肠道抗原性

Intestinal antigenicity of ovarian mucinous cystadenomas.

作者信息

Nairn R C, Wallace A C, Guli E P

出版信息

Br J Cancer. 1971 Jun;25(2):276-9. doi: 10.1038/bjc.1971.34.

Abstract

Immunofluorescent tracing by rabbit antiserum with specific reactivity against intestinal mucosa revealed cross-reaction with human ovarian mucinous cystadenoma epithelium and not with epithelium of any of several other human mucous epithelia. The mucinous cystadenoma epithelium apparently contains at least one but not all of the specific intestinal mucosal antigens. The findings support the view that such tumours are histogenetically of intestinal type, as might occur for example by unilateral intestinal development of a teratoma.

摘要

用对肠黏膜具有特异性反应性的兔抗血清进行免疫荧光追踪显示,与人卵巢黏液性囊腺瘤上皮有交叉反应,而与其他几种人黏液上皮的上皮均无交叉反应。黏液性囊腺瘤上皮显然含有至少一种但并非所有特异性肠黏膜抗原。这些发现支持了这样一种观点,即此类肿瘤在组织发生学上属于肠型,例如可能是畸胎瘤的单侧肠发育所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0653/2008443/5342df22b34b/brjcancer00359-0064-a.jpg

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引用本文的文献

本文引用的文献

1
Mucinous cystadenomas and mucinous cystadenocarcinomas of the ovary; a clinical and pathological study of 355 cases.
Cancer. 1954 Mar;7(2):302-10. doi: 10.1002/1097-0142(195403)7:2<302::aid-cncr2820070214>3.0.co;2-9.
2
Kidney-specific antigen depletion in human renal carcinomas.
Br J Cancer. 1966 Dec;20(4):756-9. doi: 10.1038/bjc.1966.87.

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