妇科肿瘤中黏液抗原的免疫组织学研究，特别涉及嗜银细胞。

Immunohistological study of mucous antigens in gynecologic tumors with special reference to argyrophil cells.

作者信息

Ueda G, Tanaka Y, Hiramatsu K, Inoue Y, Yamasaki M, Inoue M, Kurachi K, Mori T

出版信息

Int J Gynecol Pathol. 1982;1(1):41-5. doi: 10.1097/00004347-198201000-00006.

DOI:10.1097/00004347-198201000-00006

Abstract

Mucinous tumors of the ovary and adenocarcinomas of the female genital tract with or without argyrophil cells were studied by immunohistology for mucous antigens. These were isolated from intestinal mucosa and ovarian mucinous cyst fluid. Mucous antigen, M1 which is primarily associated with ovarian mucinous cystadenoma, was found in all mucinous tumors of the ovary, adenocarcinoma of the cervix, and endometrium. Intestinal mucous antigen (IMA), which is specific for goblet cells of the normal intestinal mucosa, was detected only in a few mucinous tumors of the ovary, with or without argyrophil cells. It was concluded that, while M1 was common to glandular gynecologic neoplasms, no special relationship existed between IMA and argyrophil cells in tumors of the ovary, endometrium, and endocervix.

摘要

运用免疫组织学方法，对伴有或不伴有嗜银细胞的卵巢黏液性肿瘤及女性生殖道腺癌进行了黏液抗原研究。这些抗原是从肠黏膜和卵巢黏液性囊肿液中分离出来的。主要与卵巢黏液性囊腺瘤相关的黏液抗原M1，在所有卵巢黏液性肿瘤、子宫颈腺癌和子宫内膜癌中均有发现。正常肠黏膜杯状细胞特有的肠黏液抗原（IMA），仅在少数伴有或不伴有嗜银细胞的卵巢黏液性肿瘤中检测到。研究得出结论，虽然M1在妇科腺性肿瘤中较为常见，但在卵巢、子宫内膜和子宫颈内膜肿瘤中，IMA与嗜银细胞之间不存在特殊关系。