Bowald S, Busch C, Eriksson I
Surgery. 1979 Nov;86(5):722-9.
A suture mesh of polyglactin 910 [Vicryl (polyglactin 910) suture mesh] was placed as a patch graft into the thoracic aorta of 23 growing pigs. In three other pigs the mesh was grafted in the form of a tube to replace a short aortic defect. The biological processes taking place in the grafted area were studied by morphological methods. The following observations were made: (1) Hemostasis readily occurred by fibrin, platelet, and erythrocyte embedding of the mesh. (2) Early outgrowth of smooth muscle cells around the mesh took place from the normal aortic media and from a newly formed subintimal smooth muscle layer. (3) The newly formed arterial tissue was completely endothelialized within 20 days. (4) The polyglactin mesh had disappeared almost completely at 40 days, but the new wall seemed to retain sufficient strength throughout the observation time. (5) Only irregular deposition of elastic fibrils occurred, but in other respects the new tissue structurally resembled normal arterial tissue.
将聚乙交酯910缝线网[薇乔(聚乙交酯910)缝线网]作为补片移植物植入23头生长猪的胸主动脉。在另外3头猪中,将该网以管状形式移植以替代一段短的主动脉缺损。通过形态学方法研究了移植区域发生的生物学过程。得出以下观察结果:(1)通过纤维蛋白、血小板和红细胞包埋该网,止血很容易发生。(2)网周围的平滑肌细胞早期从正常主动脉中膜和新形成的内膜下平滑肌层生长出来。(3)新形成的动脉组织在20天内完全内皮化。(4)聚乙交酯网在40天时几乎完全消失,但新形成的管壁在整个观察期内似乎保持了足够的强度。(5)仅发生了弹性纤维的不规则沉积,但在其他方面,新组织在结构上类似于正常动脉组织。