HL-A 相同的无关个体在混合淋巴细胞培养试验中的反应。
Response of HL-A identical unrelated individuals in the mixed lymphocyte culture test.
作者信息
Johnston J M, Bashir H V
出版信息
Br Med J. 1971 Dec 4;4(5787):581-4. doi: 10.1136/bmj.4.5787.581.
Abstract
The immunological responsiveness as measured in the mixed lymphocyte culture test has been studied in 13 pairs of HL-A identical unrelated individuals. In all combinations stimulation occurred and it was frequently of a similar magnitude to that observed against non-HL-A identical subjects.It is postulated that another locus, adjacent to the HL-A locus, is also responsible for the non-stimulation observed between HL-A identical siblings, and that observations made in the related situation should not be transposed to the unrelated situation without some reservation.
摘要
在13对HL - A相同的无关个体中，研究了混合淋巴细胞培养试验所测定的免疫反应性。在所有组合中均出现了刺激反应，其强度常常与针对非HL - A相同个体所观察到的相似。据推测，与HL - A基因座相邻的另一个基因座也导致了HL - A相同的同胞之间观察到的无刺激反应，并且在相关情况下所做的观察结果，若无保留则不应转用于无关情况。
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