Amos D B, Bach F H
J Exp Med. 1968 Oct 1;128(4):623-37. doi: 10.1084/jem.128.4.623.
The evidence is reviewed that a single genetic system, the major histocompatibility locus in man, HL-A, determines most of the antigens measured by presently available leukocyte isoantisera, and also controls reactivity in one-way mixed leucocyte culture tests. Studies in 12 families are presented to support this conclusion. Some interesting exceptions to the general typing-MLC tests correlation are presented and discussed.
现有证据表明,单一的遗传系统,即人类的主要组织相容性位点HL - A,决定了目前可用的白细胞同种抗血清所检测的大多数抗原,并且还控制单向混合淋巴细胞培养试验中的反应性。本文呈现了对12个家庭的研究以支持这一结论。文中还提出并讨论了一般分型与混合淋巴细胞培养试验相关性的一些有趣的例外情况。