Sauerbier W, Schweiger M, Herrlich P
J Virol. 1971 Nov;8(5):613-8. doi: 10.1128/JVI.8.5.613-618.1971.
Synthesis of early T4 protein, which is normally shut off at 10 min after infection, continues until lysis when host cells have been preinfected with T3 sam(+). In host cells preinfected with T3 sam(-), synthesis of early enzymes is shut off as normal. Thus, S-adenosylmethionine is required for the turnoff of early T4 functions (at least when host cells have been preinfected with T3).
早期T4蛋白的合成通常在感染后10分钟停止,但当宿主细胞预先感染T3 sam(+)时,该合成会持续到细胞裂解。在预先感染T3 sam(-)的宿主细胞中,早期酶的合成如正常情况一样停止。因此,S-腺苷甲硫氨酸是关闭早期T4功能所必需的(至少当宿主细胞预先感染T3时)。