Wilkins A, Gallant J, Harada B
J Bacteriol. 1971 Dec;108(3):1424-6. doi: 10.1128/jb.108.3.1424-1426.1971.
We have infected Escherichia coli strain B3 with F' factors carrying different lengths of the K-12 chromosome. When the F' factor carries the tsx to purE segment, the resulting hybrid merodiploid shows increased sensitivity to thymineless death, although leaky deoxyribonucleic acid synthesis is unaffected, as well as increased sensitivity to ultraviolet irradiation. The dominant or partially dominant character of the effect indicates that it is not a product of allelic differences between E. coli K and B at either ras or lon.
我们用携带不同长度K - 12染色体的F'因子感染了大肠杆菌B3菌株。当F'因子携带tsx到purE片段时，产生的杂种部分二倍体对胸腺嘧啶饥饿致死表现出更高的敏感性，尽管渗漏性脱氧核糖核酸合成未受影响，并且对紫外线照射也表现出更高的敏感性。这种效应的显性或部分显性特征表明，它不是大肠杆菌K和B在ras或lon处等位基因差异的产物。
