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[完整及交感神经切除兔胃平滑肌中己糖激酶和乳酸脱氢酶活性及同工酶组成]

[Hexokinase and lactate dehydrogenase activity and isoenzymatic makeup of the smooth gastric muscle in intact and sympathectomized rabbits].

作者信息

Pleskov V M, Saakian I L, Ogurtsov R P

出版信息

Vopr Med Khim. 1979 Sep-Oct;25(5):560-5.

PMID:494539
Abstract

After immunological sympathectomy in rabbits activity and isoenzyme spectra of hexokinase (HK) and lactate dehydrogenase (LDH) were studied in smooth muscle of stomach. Activity of KH in the muscles was statistically significant due to increase in content of a single isoenzyme of HK occurring in the tissue. Activity o LDH was unaltered. However the isoenzyme apectrum of the enzyme was changed: content of M-subunits was decreased and the content of H-subunits was increased. These alterations may lead to an increase in redox potential in cells of the tissues.

摘要

在对兔子进行免疫性交感神经切除术后,研究了胃平滑肌中己糖激酶(HK)和乳酸脱氢酶(LDH)的活性及同工酶谱。由于组织中出现的单一HK同工酶含量增加,肌肉中HK的活性具有统计学意义。LDH的活性未改变。然而,该酶的同工酶谱发生了变化:M亚基的含量降低,H亚基的含量增加。这些改变可能导致组织细胞中氧化还原电位升高。

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