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多凝集红细胞和癌细胞上T抗原的表达：T激活红细胞、抗T凝集素、抗T吸附人血清及纯化抗T抗体的制备

Expression of T-antigen on polyagglutinable erythrocytes and carcinoma cells: preparation of T-activated erythrocytes, anti-T lectin, anti-T absorbed human serum and purified anti-T antibody.

作者信息

Howard D R

出版信息

Vox Sang. 1979;37(2):107-10. doi: 10.1111/j.1423-0410.1979.tb02279.x.

DOI:10.1111/j.1423-0410.1979.tb02279.x
PMID:494582
Abstract

Recent interest has been revived in the human MN blood group system due to the discovery of the MN precursor substance (T-antigen) on certain malignant, but not benign or normal tissues. Methods for preparing T-activated erythrocytes, anti-T lectin, anti-T absorbed human serum and purified anti-T antibody are described and should be useful not only to the researcher involved in this new line of investigation, but also to the routine blood bank faced with the occasional problem of erythrocyte polyagglitinability.

摘要

由于在某些恶性组织而非良性或正常组织上发现了MN前体物质（T抗原），人类MN血型系统最近重新引起了人们的关注。本文描述了制备T激活红细胞、抗T凝集素、抗T吸收人血清和纯化抗T抗体的方法，这些方法不仅对参与这一新研究领域的研究人员有用，而且对偶尔遇到红细胞多凝集性问题的常规血库也有用。

相似文献

1
Expression of T-antigen on polyagglutinable erythrocytes and carcinoma cells: preparation of T-activated erythrocytes, anti-T lectin, anti-T absorbed human serum and purified anti-T antibody.多凝集红细胞和癌细胞上T抗原的表达：T激活红细胞、抗T凝集素、抗T吸附人血清及纯化抗T抗体的制备
Vox Sang. 1979;37(2):107-10. doi: 10.1111/j.1423-0410.1979.tb02279.x.
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Deantigenation of human erythrocytes by bacterial glycosidases--evidence for the noninvolvement of medium-sized glycosphingolipids in the Dolichos biflorus lectin hemagglutination.细菌糖苷酶对人红细胞的去抗原作用——关于中等大小糖鞘脂不参与双花扁豆凝集素血细胞凝集作用的证据
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A review of serologic problems caused by polyagglutinable red cells.多凝集红细胞引起的血清学问题综述。
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Specificity of reagents directed to the Thomsen-Friedenreich antigen and their capacity to bind to the surface of human carcinoma cell lines.针对桑德森-弗里登赖希抗原的试剂特异性及其与人癌细胞系表面结合的能力。
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[The preparation of an anti-A reagent from the lectin of hairy vetch (Vicia villosa) for detecting antigen A in human erythrocytes and saliva].[从毛苕子（Vicia villosa）凝集素制备抗A试剂用于检测人红细胞和唾液中的A抗原]
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Persistent polyagglutinability in vivo unrelated to T-anigen activation.体内持续性多凝集性与T抗原激活无关。
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引用本文的文献

1
A case of polyagglutination.一例多凝集现象。
Z Rechtsmed. 1983;90(2):147-52. doi: 10.1007/BF02092299.
2
Tn polyagglutinability occurring in a patient with B cell lymphoma.B细胞淋巴瘤患者中出现的Tn多凝集性。
Blut. 1985 Nov;51(5):355-60. doi: 10.1007/BF00320046.