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[腐败物质中δ-氨基戊酸的鉴定及其意义(作者译)]

[Identification and significance of delta-aminovaleric acid in putrefaction materials (author's transl)].

作者信息

Bonte W, Theusner J

出版信息

Z Rechtsmed. 1979 Jul 17;83(2):139-46. doi: 10.1007/BF02092270.

DOI:10.1007/BF02092270
PMID:494814
Abstract

During former putrefaction experiments regularly a proteogenic substance has been found which by means of modern analytical methods now was identified as delta-aminovaleric acid (DAVA). DAVA seems to appear in guinea pig as well as human organs and some body fluids under experimental conditions never before the 3rd (20 degrees C) to 5th day (10 degrees C). It is characterized by statistically significant increases until the end of the 2nd (20 degrees C) to 5th week (10 degrees C) and relatively stable values thereafter. Considering storage temperature measurement of DAVA concentration can be of relevance for the estimation of the time of death in cases of putrescent corpses.

摘要

在以往的腐败实验中,经常会发现一种蛋白原性物质,通过现代分析方法,现在已将其鉴定为δ-氨基戊酸(DAVA)。在实验条件下,豚鼠以及人体器官和一些体液中似乎在第3天(20摄氏度)至第5天(10摄氏度)之前从未出现过DAVA。其特征是在第2周(20摄氏度)至第5周(10摄氏度)结束前有统计学上的显著增加,此后数值相对稳定。考虑到储存温度,DAVA浓度的测量对于腐尸案件中死亡时间的估计可能具有相关性。

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本文引用的文献

1
The metabolism of lysine.赖氨酸的代谢
Biochem J. 1944;38(1):119-25. doi: 10.1042/bj0380119.
2
Studies in the metabolism of the strict anaerobes (genus Clostridium): Further experiments on the coupled reactions between pairs of amino-acids induced by Cl. sporogenes.严格厌氧菌(梭菌属)的代谢研究:关于生孢梭菌诱导的氨基酸对之间偶联反应的进一步实验。
Biochem J. 1936 Oct;30(10):1934-46. doi: 10.1042/bj0301934.
3
Studies in the metabolism of the strict anaerobes (Genus Clostridium): The reduction of proline by Cl. sporogenes.严格厌氧菌(梭菌属)的代谢研究:生孢梭菌对脯氨酸的还原作用。
Biochem J. 1935 Feb;29(2):288-90. doi: 10.1042/bj0290288.
4
Studies in the metabolism of the strict anaerobes (genus Clostridium): The chemical reactions by which Cl. sporogenes obtains its energy.严格厌氧菌(梭菌属)的代谢研究:生孢梭菌获取能量的化学反应。
Biochem J. 1934;28(5):1746-59. doi: 10.1042/bj0281746.
5
The Utilization of Amino Acids and of Glucose by Clostridium botulinum.肉毒梭菌对氨基酸和葡萄糖的利用
J Bacteriol. 1940 May;39(5):485-97. doi: 10.1128/jb.39.5.485-497.1940.
6
L-Lysine oxidase, a new oxygenase.L-赖氨酸氧化酶,一种新型加氧酶。
J Biochem. 1961 Aug;50:118-21. doi: 10.1093/oxfordjournals.jbchem.a127418.
7
Studies on the enzymic reduction of amino acids. II. Purification and properties of D-proline reductase and a proline racemase from Clostridium sticklandii.氨基酸的酶促还原研究。II. 来自斯氏梭菌的D-脯氨酸还原酶和脯氨酸消旋酶的纯化及性质
J Biol Chem. 1957 Oct;228(2):983-97.
8
[Quantitative investigation of the amino acid levels in putrefying liver (author's transl)].
Z Rechtsmed. 1975 Dec 10;76(4):293-306. doi: 10.1007/BF02114690.
9
Postmortem dating of putrefied material through ptomaine estimation.通过尸碱估计对腐败物质进行死后时间推断。
J Forensic Sci. 1977 Jul;22(3):558-72.
10
[Postmortem changes in the concentration of free amino acids in the vitreous body].[玻璃体中游离氨基酸浓度的死后变化]
Beitr Gerichtl Med. 1977;35:133-43.