Hansen-Leth C
Acta Orthop Scand. 1979 Aug;50(4):399-406. doi: 10.3109/17453677908989782.
With the aid of microangiography the vascularization in the amputation stumps of 108 rabbits was studied, both in extremities with normal circulation and in those supplied with collaterals. It was found that the vascularization of the normal leg was altered by amputation, with the development of newly-formed, pathological, spirally-twisted vessels. Closure of the stump with myoplasty, however, counteracted this vessel formation, and hypervascularization took place through normal arteries. After amputation of extremities supplied with collaterals, the influence of amputation on collateral function and vascularization in the amputation stump was dependent on the time interval between arterial occlusion and amputation.
借助微血管造影术，对108只兔子截肢残端的血管形成情况进行了研究，研究对象包括血液循环正常的肢体以及有侧支循环的肢体。研究发现，正常肢体截肢后血管形成发生改变，出现了新形成的、病理性的、螺旋状扭曲的血管。然而，通过肌成形术闭合残端可抵消这种血管形成，并且通过正常动脉发生了血管过度形成。在有侧支循环的肢体截肢后，截肢对侧支循环功能及截肢残端血管形成的影响取决于动脉闭塞与截肢之间的时间间隔。
