Hansen-Leth C, Karle A
Acta Orthop Scand. 1978 Oct;49(5):457-63. doi: 10.3109/17453677808993262.
The vascular changes in rabbits after amputation were studied in vivo with arteriography, after intracardial injection of contrast. In the amputated extremity an initial vasoconstriction of the arteries was found. Thereafter changes were observed in arteries and veins, both in the operated and contralateral extremities, depending on the level of amputation and the manner in which the stump was closed. After amputation distally on the extremity and after stump closure without myoplasty arteriovenous shunting was observed in the amputation stump. Arteriovenous shunts were not seen after knee disarticulation and after proximal amputation on crus with myoplasty. Inactivity of the muscles in the amputation stump is supposed to be the cause of the shunt formation. After mid-femur amputation a permanent vasoconstriction of the femoral artery was observed, whereas artery dilation was seen when amputation on the femur was combined with plugging of the medullary cavity.
通过心内注射造影剂后进行动脉造影，在体内研究了兔截肢后的血管变化。在截肢肢体中，发现动脉最初出现血管收缩。此后，根据截肢水平和残端闭合方式，在手术肢体和对侧肢体的动脉和静脉中均观察到了变化。在肢体远端截肢且残端闭合未行肌成形术之后，在截肢残端观察到动静脉分流。膝关节离断后以及小腿近端截肢并行肌成形术后未见到动静脉分流。截肢残端肌肉不活动被认为是分流形成的原因。股骨中段截肢后，观察到股动脉永久性血管收缩，而当股骨截肢合并髓腔堵塞时则可见动脉扩张。
