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The hypothalamic and neurohypophysial vasopressin content as influenced by diphenylhydantoin in dehydrated rats.

作者信息

Niewiadomski J S

出版信息

Acta Physiol Pol. 1979 Mar-Apr;30(3):351-8.

PMID:495139
Abstract

Rats dehydrated up to 8 days were treated with diphenylhydantoin given intraperitoneally in daily doses of 10 mg/100 g of the initial body weight. The single dose of diphenylhydantoin diminished the vasopressin content in the hypothalamus and neurohypophysis of normally hydrated rats. Under conditions of severe dehydration (8 days), DPH treatment resulted in a more marked decrease of vasopressin in the hypothalamo-neurohypophysial system.

摘要

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