通过去除钙离子使上皮细胞膜连接解离。
Uncoupling of an epithelial cell membrane junction by calcium-ion removal.
作者信息
Nakas M, Higashino S, Loewenstein W R
出版信息
Science. 1966 Jan 7;151(3706):89-91. doi: 10.1126/science.151.3706.89.
Calcium takes part in maintaining ion communication between salivary gland cells (Chironomus thummi). Its withdrawal from the cell systems results in virtual disconnection of ion communication, at Ca(++) concentrations which do not noticeably affect cell adhesion. The junctional membrane surfaces. which are normally quite freely permeable to ions, become as impermeable as the nonjunctional membrane surfaces; each cell seals itself off irreversibly as a unit. In maintaining ion communication Mg(++) substitutes for Ca(++)
钙参与维持唾液腺细胞（摇蚊）之间的离子通讯。从细胞系统中去除钙会导致离子通讯实际上的中断，此时钙离子浓度并不会显著影响细胞黏附。通常对离子具有相当高通透性的连接膜表面，会变得与非连接膜表面一样不可渗透；每个细胞作为一个单元不可逆地自我封闭起来。在维持离子通讯方面，镁离子可以替代钙离子。
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