Halpern B N, Ky T, Robert B
Immunology. 1967 Mar;12(3):247-58.
An exceptionally rare case of spontaneous allergic sensitization to a glycoprotein rich in sialic acid and present in human seminal fluid is described in a woman. An anaphylactic reaction, consisting of giant urticaria, oedema, asthma, uterine pain and cardiovascular collapse followed within minutes of coitus. A high degree of atopic hypersensitivity was shown by skin reactions to human seminal fluid, but not to that of animal origin. Passive transfer of the hypersensitivity to man and monkey was successful and the responsible antibody was shown to be reagin-like and associated with the group of γA-globulins.
本文描述了一例极为罕见的病例，一名女性对富含唾液酸且存在于人类精液中的糖蛋白发生了自发性过敏致敏反应。性交后几分钟内便出现了过敏反应，包括巨大荨麻疹、水肿、哮喘、子宫疼痛和心血管虚脱。皮肤对人类精液有反应，但对动物来源的精液无反应，显示出高度的特应性超敏反应。这种超敏反应成功地被动转移给了人和猴子，且证实起作用的抗体类似反应素，并与γA球蛋白组相关。
