Sohier J, Bousquet B, Garnier J P, Escande C, Ramelet A A, Dreux C, Civatte J
Ann Dermatol Venereol. 1979 May;106(5):491-4.
We studied a bullous photodermatosis recurring for two years in a old woman. The eruption was diagnosed as a pellagra-like syndrome on tryptophan loading test disorders without any other cause of sun sensitivity. The static and dynamic metabolic investigation was centered on tryptophan and vitaminic coenzymes which mediate catabolic reactions. The defect are located on the kinurenin pathway. The discussion analyses the possible relations between the dermatosis and the biological disturbances observed.
我们研究了一位老年女性身上反复发作两年的大疱性光皮肤病。在色氨酸负荷试验紊乱且无其他日光敏感原因的情况下，该皮疹被诊断为类糙皮病综合征。静态和动态代谢研究集中在介导分解代谢反应的色氨酸和维生素辅酶上。缺陷位于犬尿氨酸途径。讨论分析了观察到的皮肤病与生物紊乱之间可能的关系。
