Scheunig G, Horn K H, Mehnert W H
Arch Geschwulstforsch. 1979;49(3):220-8.
In a long-term experiment the induction of tumors in rats after oral application of aminopyrine and nitrite by gastric intubation was investigated. The animals treated with aminopyrine and nitrite (test-group) had an incidence of different types of liver tumors of 96% in females and 97% in males. The percentage of liver tumors was increased significantly in the test-group in comparison to all control-groups. Besides the tumors of the liver other types of tumors were stated to a minor degree, but there was no difference between the test-group and the control-groups.
在一项长期实验中，研究了通过胃管向大鼠口服氨基比林和亚硝酸盐后诱发肿瘤的情况。用氨基比林和亚硝酸盐处理的动物（试验组）中，雌性大鼠不同类型肝肿瘤的发生率为96%，雄性大鼠为97%。与所有对照组相比，试验组肝肿瘤的百分比显著增加。除了肝肿瘤外，其他类型的肿瘤也有少量发生，但试验组和对照组之间没有差异。
