Gibel W, Lohs K, Horn K H, Wildner G P, Hoffmann F
Arch Geschwulstforsch. 1976;46(6):437-42.
Wistar rats evolved many malignant tumors of different localisation. The tumors grew in the time of 8-14 months after oral application of asbestos filters which contained 53% Chrysotile asbestos. The number of tumors was statistically significant different not only in comparison to a control group which got talc only, but also to an untreated control group. The localisation of the tumors varied and so conclusions about organ specifity can not be drawn, when asbestos is applicated orally.
Wistar大鼠出现了许多不同部位的恶性肿瘤。在口服含有53%温石棉的石棉滤器后8至14个月内肿瘤生长。肿瘤数量不仅与仅接受滑石粉的对照组相比有统计学显著差异,而且与未处理的对照组相比也有显著差异。肿瘤的部位各不相同,因此口服石棉时无法得出关于器官特异性的结论。