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Behavioral effects in monkeys of racemates of two biologically active marijuana constituents.

作者信息

Scheckel C L, Boff E, Dahlen P, Smart T

出版信息

Science. 1968 Jun 28;160(3835):1467-9. doi: 10.1126/science.160.3835.1467.

DOI:10.1126/science.160.3835.1467
PMID:4968256
Abstract

Both dl-Delta(8)- and dl-Delta(9)-tetrahydrocannabinol produced marked alterations of behavior in rhesus and squirrel monkeys. Squirrel monkeys appeared to have visual hallucinations. Continuous avoidance behavior of squirrel monkeys was stimulated by both drugs, but high doses of dl-Delta(9)-tetrahydrocannabinol also caused depression after the stimulant phase. Complex behavior involving memory and visual discrimination in rhesus monkeys was markedly disrupted by both drugs.

摘要

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