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皮肤癣菌的免疫学研究。3. 对中性多糖与兔抗昆克小孢子菌、许兰毛癣菌、红色毛癣菌、指间毛癣菌和颗粒状毛癣菌抗血清反应性的进一步分析。

Immunological studies on dermatophytes. 3. Further analyses of the reactivities of neutral polysaccharides with rabbit antisera to Microsporum quinckeanum, Trichophyton schoenleinii, Trichophyton rubrum, Trichophyton interdigitale, and Trichophyton granulosum.

作者信息

Grappel S F, Blank F, Bishop C T

出版信息

J Bacteriol. 1968 Jul;96(1):70-5. doi: 10.1128/jb.96.1.70-75.1968.

DOI:10.1128/jb.96.1.70-75.1968
PMID:4969608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC252254/
Abstract

The serological reactivities of polysaccharides isolated from five species of dermatophytes, Microsporum quinckeanum, Trichophyton granulosum, T. interdigitale, T. rubrum, and T. schoenleinii, with rabbit antisera to these species were studied qualitatively by precipitation in gel and quantitatively by complement-fixation analyses. Significant differences in the serological reactivities of the galactomannans I were detected with antisera to T. schoenleinii and T. interdigitale. The differences appeared to be related to the specificity of these antisera for the galactofuranose residues in the polysaccharides. Antisera to M. quinckeanum, T. granulosum, or T. rubrum did not detect differences between the galactomannans I. The serological reactivities of the galactomannans II were different with each of the five antisera. The reactivities of the glucans could be correlated with the amount of alpha 1 --> 6 linked glucopyranose residues when antisera to T. schoenleinii and M. quinckeanum were used.

摘要

对从五种皮肤癣菌(昆克小孢子菌、颗粒状毛癣菌、指间毛癣菌、红色毛癣菌和许兰毛癣菌)中分离出的多糖与针对这些菌种的兔抗血清之间的血清学反应性进行了研究,采用凝胶沉淀法进行定性研究,并采用补体结合分析法进行定量研究。在针对许兰毛癣菌和指间毛癣菌的抗血清中,检测到了半乳甘露聚糖I血清学反应性的显著差异。这些差异似乎与这些抗血清对多糖中呋喃半乳糖残基的特异性有关。针对昆克小孢子菌、颗粒状毛癣菌或红色毛癣菌的抗血清未检测到半乳甘露聚糖I之间的差异。半乳甘露聚糖II与五种抗血清中的每一种的血清学反应性都不同。当使用针对许兰毛癣菌和昆克小孢子菌的抗血清时,葡聚糖的反应性可能与α1→6连接的吡喃葡萄糖残基的数量相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d2/252254/c2911c6ee764/jbacter00394-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d2/252254/862888c45898/jbacter00394-0107-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d2/252254/c2911c6ee764/jbacter00394-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d2/252254/862888c45898/jbacter00394-0107-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d2/252254/c2911c6ee764/jbacter00394-0108-a.jpg

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本文引用的文献

1
Immunological studies on dermatophytes. II.皮肤癣菌的免疫学研究。II.
J Bacteriol. 1968 Apr;95(4):1238-42. doi: 10.1128/jb.95.4.1238-1242.1968.
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Immunological studies on dermatophytes. I. Serological reactivities of neutral polysaccharides with rabbit antiserum to Microsporum quinckeanum.皮肤癣菌的免疫学研究。I. 中性多糖与兔抗昆克小孢子菌抗血清的血清学反应性。
J Bacteriol. 1967 Mar;93(3):1001-8. doi: 10.1128/jb.93.3.1001-1008.1967.
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Immunological studies on dermatophytes. IV. Chemical structures and serological reactivities of polysaccharides from Microsporum praecox, Trichophyton ferrugineum, Trichophyton sabouraudii, and Trichophyton tonsurans.皮肤癣菌的免疫学研究。IV. 早熟小孢子菌、铁锈色毛癣菌、萨布罗毛癣菌和断发毛癣菌多糖的化学结构与血清学反应性
J Bacteriol. 1969 Jan;97(1):23-6. doi: 10.1128/jb.97.1.23-26.1969.
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Immunology of dermatophytes and dermatophytosis.皮肤癣菌与皮肤癣菌病的免疫学
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